TTK激酶抑制剂和使用方法
本文公开了作为Mps1/TTK抑制剂的新型化合物。本文也公开了包含所述化合物的组合物以及使用所述化合物治疗患者中的各种疾病的方法。在一些实施方案中,一些这样的化合物、组合物及其用途可以用于治疗癌症。在一些实现中,所述癌症是脑癌、多形性胶质母细胞瘤、头颈癌、结肠直肠癌、胃部或胃癌、胰腺癌、黑色素瘤、膀胱癌、肾癌、肾细胞癌、乳腺癌、卵巢癌、淋巴瘤、甲状腺癌、间皮瘤、肉瘤、肺癌、非小细胞肺癌、小细胞肺癌或子宫内膜癌。
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