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№ CN121343974AInvention

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己醛糖-2-差向异构酶突变体及应用

本申请涉及生物技术领域，特别是涉及一种己醛糖‑2‑差向异构酶突变体及应用。本申请实施例的己醛糖‑2‑差向异构酶突变体及应用，该己醛糖‑2‑差向异构酶突变体在如SEQ ID NO：19所示氨基酸序列中至少一个关键位点产生有利于提高己醛糖C‑2位羟基异构化催化活性的突变；通过上述方式，该己醛糖‑2‑差向异构酶突变体表现出优异的己醛糖C‑2位羟基异构化催化活性，能够高效的将D‑葡萄糖转换为D‑甘露糖，有利于提高D‑甘露糖的合成效率。

❖杭州欣贝莱生物科技有限公司夏文豪; 王筱; 白涛; 王姗姗§ 8/10 ClaimsC12N 9/90 (2006.01), C12N 15/70 (2006.01), C12N 15/75 (2006.01) +710

№ CN121343975AInvention

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D-阿洛酮糖3-差向异构酶突变体及应用

本申请涉及生物技术领域，尤其涉及一种D‑阿洛酮糖3‑差向异构酶突变体及应用，该差向异构酶突变体在如SEQ ID NO：20所示氨基酸序列中至少一个关键位点产生突变，该突变有利于提高D‑果糖C3差向异构化形成D‑阿洛酮糖的催化活性；通过上述方式，该差向异构酶突变体表现出优异的D‑果糖C3差向异构化形成D‑阿洛酮糖的催化活性，能够高效的将D‑果糖转换为D‑阿洛酮糖，有利于提高D‑阿洛酮糖合成效率。

❖杭州欣贝莱生物科技有限公司刘毅; 王筱; 夏文豪; 白涛§ 5/10 ClaimsC12N 9/90 (2006.01), C12N 15/75 (2006.01), C12N 15/61 (2006.01) +49