RP-6306的晶型及其制备方法和用途
一种Lunresertib(也称为RP‑6306)的晶型及其制备方法和用途。其至少具有以下一种优良的特性:稳定性良好,纯度高,溶解度好,溶出好,引湿性低,流动性好,可加工性好例如可压性好、压片后的片剂更稳定,晶体形貌好,抗压性好,能稳定储存,避免药物在开发过程和储存中发生转晶,制备方法简单可靠,具有较大的开发价值。
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