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Original name record: 湖北美琪健康科技有限公司

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1 indexed patent records

№ CN121312827AInvention
Active

一种维生素k2微囊粉及其应用

本发明涉及一种维生素K2微囊粉及其应用，解决现有技术中维生素K2因微囊结构缺陷(微囊结构不规则、破碎、粘连、多孔疏松等)导致的包埋率低、稳定性差，尤其在钙复合片剂中因与钙、镁等金属离子的相容性引发的降解严重等问题。具体而言，本发明提供的维生素K2微囊粉，包括以下组分：油相组分：维生素K2、载体油、油相乳化剂、抗氧化剂；水相组分：壁材、水相乳化剂、水，其具有近球形形态、表面致密、内部实心结构、粒径分布均匀，且包埋率≥89％(HPLC法)；微囊粉加速稳定性(40℃/75％RH，6个月)保留率≥96％；基于该微囊粉制备的钙复合片剂，在同等加速条件下(40℃/75％RH，6个月)，维生素K2含量≥89％、保留率≥79％。

❖湖北美琪健康科技有限公司张建涛; 陈辅辰; 李润林; 钟启武; 黄婷; 周峰; 陈全兵; 杨军会§ 4/12 ClaimsA23L 33/15 (2016.01), A23P 10/35 (2016.01), A23L 33/165 (2016.01)12