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维罗非尼在制备治疗肾纤维化疾病药物中的应用
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8Claims · 2 independent
§ Ⅰ
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Inventor
程永现; 徐远城; 江建冰; 陶诚天
IPC Classification
A61K 31/437 (2006.01)A61K 9/08 (2006.01)A61P 13/12 (2006.01)
本发明属于药物新用途领域,更具体地,涉及维罗非尼在制备治疗肾纤维化疾病的药物中的应用。本发明首次发现维罗非尼通过结合EIF4A1蛋白来抑制肾纤维活性,可作为潜在的抗肾组织纤维化药物,为抗器官或组织纤维化药物的研究提供了新思路。
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