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一种美利曲辛中间体的制备方法
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10Claims · 4 independent
§ Ⅰ
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Inventor
章泽洲; 周正荣; 王恩; 王足兵; 吴晶; 徐丹; 朱春霞
IPC Classification
C07C 213/10 (2006.01)C07C 213/00 (2006.01)C07C 215/42 (2006.01)C07C 209/68 (2006.01)C07C 211/63 (2006.01)C07C 211/31 (2006.01)
本发明属于药物合成技术领域，具体涉及一种高纯度美利曲辛中间体1的制备方法及其基因毒性杂质的控制。本发明提供一种基因毒性杂质A或B及其制备方法和美利曲辛中间体1的制备方法。本发明所述方法收率高，纯度高，操作简单，条件温和，适合工业化大生产。
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