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基于酚酸脂质的阳离子脂质
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10Claims · 5 independent
§ Ⅰ
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Inventor
S·卡夫; F·德罗萨; A·旺威拉翁; S·卡马卡
IPC Classification
C07C 229/12 (2006.01)C07C 229/16 (2006.01)C07D 295/088 (2006.01)C07D 213/30 (2006.01)
本发明部分地提供了式(I)和其子式的酚酸脂质化合物或其药学上可接受的盐。本文提供的化合物可用于递送和表达mRNA和所编码蛋白质,例如作为脂质体递送媒剂的组分,并因此可用于治疗各种疾病、病症和病状,如与一种或多种蛋白质的缺乏相关的疾病、病症和病状。
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