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GSPT1降解剂及其应用
InventionActive
8Claims · 3 independent
§ Ⅰ
Dossier Overview
Inventor
郑国闯; 张小猛; 田新磊; 高尚; 潘涛
IPC Classification
C07D 401/14 (2006.01)C07D 405/14 (2006.01)C07D 487/06 (2006.01)C07D 498/06 (2006.01)C07D 471/10 (2006.01)A61K 31/4747 (2006.01)A61K 31/454 (2006.01)A61K 31/4545 (2006.01)A61K 31/4985 (2006.01)A61K 31/5383 (2006.01)A61P 35/00 (2006.01)
本发明属于医药化学领域,具体涉及作为GSPT1降解剂的式(I)化合物或其药学上可接受的盐、异构体、溶剂化物、结晶或前药,它们的制备方法以及含有这些化合物的药物组合物和这些化合物或组合物用于治疗降解GSPT1有益的疾病如癌症的用途。
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