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TREM2激动剂及其制备方法和用途

InventionActive
9Claims · 3 independent
§ Ⅰ

Dossier Overview

Inventor

张睿; 逄龙; 黄丹丹; 张晓敏; 孙伟杰

IPC Classification

C07D 471/04 (2006.01)C07D 487/04 (2006.01)A61K 31/437 (2006.01)A61K 31/519 (2006.01)A61K 31/53 (2006.01)C07D 471/14 (2006.01)C07D 491/147 (2006.01)A61P 25/28 (2006.01)A61P 25/16 (2006.01)A61P 25/00 (2006.01)A61P 21/00 (2006.01)A61P 9/10 (2006.01)

本发明提供了TREM2激动剂,其可用于预防和/或治疗TREM2相关的疾病,包括阿尔兹海默症、帕金森、多囊性脂膜样骨发育不良并硬化性白质脑病、脑卒中、遗传性弥漫性白质脑病伴轴索球样变、肌萎缩侧索硬化等。

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