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一种布鲁氏菌CTL抗原表位肽及其应用

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9Claims · 7 independent
§ Ⅰ

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Inventor

梁瑞英; 汤新明; 丁家波; 杨晓雯; 蒋卉; 李朋

IPC Classification

C07K 14/23 (2006.01)A61K 39/10 (2006.01)A61P 31/04 (2006.01)G01N 33/569 (2006.01)

本发明公开了一种布鲁氏菌CTL抗原表位肽及其应用,其为以下任一或多个表位多肽,所述表位多肽的氨基酸序列如SEQIDNO.1‑3的所示;本发明精准激活CTL免疫应答,契合布鲁氏菌胞内感染的免疫防御需求,为布鲁氏菌新型亚单位疫苗提供核心成分,规避传统减毒活疫苗毒力返祖、干扰诊断等风险。

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