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一种识别磷酸化ERK的抗体

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14Claims · 9 independent
§ Ⅰ

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Inventor

任鹏举; 王鹏; 陶维红

IPC Classification

C07K 16/40 (2006.01)C12N 9/12 (2006.01)C12N 15/13 (2006.01)G01N 33/573 (2006.01)G01N 33/575 (2026.01)G01N 33/57545 (2026.01)G01N 33/57535 (2026.01)G01N 33/57515 (2026.01)G01N 33/5752 (2026.01)G01N 33/577 (2006.01)A61K 39/395 (2006.01)A61P 35/00 (2006.01)

本发明公开了能够识别磷酸化细胞外调节蛋白激酶(p‑ERK)的抗体及其制备方法。所述抗体能够高特异性和高灵敏度地与磷酸化的ERK结合。利用本发明的抗体可以深入研究蛋白激酶ERK的磷酸化活化对细胞正常增殖及癌变的影响机制,从而对疾病的检测、预防及治疗发挥更大的作用。

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