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一种用于生产N-乙酰神经氨酸的基因工程菌及构建方法和应用
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10Claims · 3 independent
§ Ⅰ
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Inventor
刘振云; 徐惊东; 张璇
IPC Classification
C12N 1/21 (2006.01)C12N 15/70 (2006.01)C12N 9/10 (2006.01)C12N 9/90 (2006.01)C12N 15/54 (2006.01)C12N 15/61 (2006.01)C12N 15/52 (2006.01)C12P 19/26 (2006.01)C12R 1/19 (2006.01)
本发明涉及一种用于生产N‑乙酰神经氨酸的基因工程菌及构建方法和应用。所述基因工程菌表达了外源的N‑乙酰神经氨酸合酶NeuB；所述外源的N‑乙酰神经氨酸合酶NeuB来源于维隆气单胞菌、疾卡氏菌、嗜血杆菌属和肝弧菌中的一种或多种。本发明提供的菌株能够提高大肠杆菌的合成N‑乙酰神经氨酸的产量。
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