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一种生产吡咯喹啉醌的工程菌及其制备方法
InventionActive
10Claims · 6 independent
§ Ⅰ
Dossier Overview
Inventor
韩双; 蒋兴; 陈志文; 应雪肖; 陈峰
IPC Classification
C12N 1/21 (2006.01)C12N 15/74 (2006.01)C12N 15/52 (2006.01)C12P 17/18 (2006.01)C12R 1/01 (2006.01)
本发明涉及PQQ生产领域,具体涉及一种生产吡咯喹啉醌的工程菌及其制备方法。本发明通过使用不同的广宿主穿梭载体,在脱氮生丝微菌中表达PQQ合成相关基因簇,成功构建了高产PQQ的脱氮生丝微菌工程菌,该工程菌具有生长迅速、发酵产量高等特点,为实现PQQ绿色生产奠定了基础。
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