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转氨酶突变体及其应用
InventionActive
7Claims · 4 independent
§ Ⅰ
Dossier Overview
Applicant
国药集团威奇达药业有限公司
Inventor
朱慧; 强济宇; 何源; 冯涛; 范虎; 张慧洁
IPC Classification
C12N 9/10 (2006.01)C12N 15/54 (2006.01)C12N 15/70 (2006.01)C12P 17/18 (2006.01)C12R 1/19 (2006.01)
本发明属于生物工程技术领域,具体涉及一种转氨酶突变体及其应用,本发明制备所得的转氨酶突变体SEQ ID NO:37相较于现有的转氨酶突变其具有更高的酶活力,可以以西格列汀前体酮为底物制备西格列汀,达到直接降低酶的使用成本和反应时间,提高生产效率的技术效果。
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