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甲泼尼龙中间体双羟物及其制备方法
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10Claims · 2 independent
§ Ⅰ
Dossier Overview
Inventor
孔张海; 陈俊; 赵青沙; 王敏强; 冯建
Filing Date
Jun 3, 2026
Publication Date
Oct 16, 2026
IPC Classification
C07J 7/00 (2006.01)
本发明提供了一种甲泼尼龙中间体双羟物及其制备方法。该制备方法，包括如下步骤：以式Ⅰ所示化合物氢化可的松中间体氯化物为原料，依次进行上溴羟反应、脱溴氯反应，制得甲泼尼龙中间体双羟物III。该制备方法将传统的脱氯与脱溴两步反应合并为一步脱溴氯反应，显著缩短了合成路线，简化了操作流程，提高了生产效率。
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