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And-1表达促进剂用于制备防治肝损伤的药物的用途
InventionUnknown
7Claims · 2 independent
§ Ⅰ
Dossier Overview
Inventor
李永明; 麻彤辉; 张雅琦; 李玲艳
Filing Date
Apr 10, 2025
Publication Date
Oct 20, 2026
IPC Classification
A61K 45/00 (2006.01)A61P 1/16 (2006.01)A61K 38/17 (2006.01)
本发明公开了And‑1表达促进剂用于制备防治肝损伤的药物的用途。本发明发现，敲除或沉默And‑1会明显加重肝损伤，过表达And‑1可以明显改善肝损伤，And‑1表达促进剂具有开发成防治肝损伤的药物的前景，And‑1基因或蛋白可以作为药物作用靶点用于筛选发现防治肝损伤的药物；其中，And‑1表达促进剂指促进And‑1表达的物质，可以为促进And‑1表达的核苷酸序列或含有该核苷酸序列的载体，也可以为促进And‑1表达的化合物。
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