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一类土黄酮肉桂酸衍生物及其应用

InventionUnknown
10Claims · 1 independent
§ Ⅰ

Dossier Overview

Inventor

陈文豪; 李文杏; 惠阳

Filing Date

Aug 20, 2026

Publication Date

Oct 20, 2026

IPC Classification

C07C 69/618 (2006.01)C07C 69/65 (2006.01)C07C 69/736 (2006.01)C07C 207/00 (2006.01)C07C 67/08 (2006.01)C07C 201/00 (2006.01)A61K 31/216 (2006.01)A61P 35/00 (2006.01)A61P 1/16 (2006.01)

本发明公开了一类土黄酮肉桂酸衍生物的制备方法及其应用,所述土黄酮肉桂酸衍生物为化合物1a~1q。经细胞毒性试验表明:化合物1a~1q在一定程度上抑制肿瘤细胞增殖活性,可以进一步开发为制备抗癌药物,尤其是化合物1i,抗肝癌细胞Hep G2活性强于阳性对照阿霉素,可在制备抗肝细胞癌药物中的应用。

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