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嘧啶并[6,1-a]异喹啉-4-酮衍生物及其用途

InventionUnknown
16Claims · 2 independent
§ Ⅰ

Dossier Overview

Applicant

广州呼吸药物工程技术有限公司

广州呼吸药物工程技术有限公司 · View all patentsPatent applicant records

Inventor

吴志明; 谢强敏

Filing Date

Apr 10, 2025

Publication Date

Oct 20, 2026

IPC Classification

C07D 471/04 (2006.01)A61K 31/519 (2006.01)A61P 1/04 (2006.01)A61P 11/00 (2006.01)A61P 11/02 (2006.01)A61P 11/06 (2006.01)A61P 11/08 (2006.01)A61P 13/12 (2006.01)A61P 21/00 (2006.01)A61P 9/00 (2006.01)A61P 25/00 (2006.01)A61P 27/02 (2006.01)A61P 29/00 (2006.01)A61P 3/10 (2006.01)A61P 31/04 (2006.01)A61P 31/12 (2006.01)A61P 37/08 (2006.01)

本发明涉及一种嘧啶并[6,1‑a]异喹啉‑4‑酮衍生物及其用途。本发明的嘧啶并[6,1‑a]异喹啉‑4‑酮衍生物的结构式如式(I)所示：其中，R、R、R、X、Y如说明书所述。本发明的化合物可以同时抑制PDE3和PDE4，且与现有的PDE3和PDE4双靶点抑制剂相比较，效果更佳。

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