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白介素-1受体相关激酶的双官能降解物及其治疗用途

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新锐思生物制药股份有限公司; 吉利德科学公司

新锐思生物制药股份有限公司 · View all patents 吉利德科学公司 · View all patents Patent applicant records

Inventor

W·帕尔默; J·吴; J·李; K·奥兹博亚; T·凯恩

Filing Date

Aug 18, 2022

Publication Date

Oct 20, 2026

IPC Classification

C07D 487/04 (2006.01)C07D 519/00 (2006.01)A61K 31/5025 (2006.01)A61K 31/506 (2006.01)A61K 31/529 (2006.01)A61P 35/00 (2006.01)A61P 3/00 (2006.01)A61P 29/00 (2006.01)A61P 13/12 (2006.01)

本公开提供了通过泛素蛋白酶体途径作为IRAK4降解物的双官能化合物，以及用于治疗由IRAK4调节的疾病的方法。

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白介素-1受体相关激酶的双官能降解物及其治疗用途

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