CNIPA.AI
Back to Search
Dossier

IOX4在干细胞诱导分化软骨细胞中的应用

InventionUnknown
9Claims · 6 independent
§ Ⅰ

Dossier Overview

Inventor

陆品帆; 王宗起; 袁亚林; 孙丹丹; 刘璐; 叶凌涛

Filing Date

Nov 16, 2023

Publication Date

Oct 27, 2026

IPC Classification

C12N 5/077 (2010.01)

本发明涉及生物医药工程技术领域,提供了IOX4在干细胞诱导分化软骨细胞中的应用。IOX4通过抑制HIF1的降解,提高脐带间充质干细胞增殖,促进人脐带间充质干细胞的软骨分化,缩短诱导软骨细胞时间。结果显示,加入IOX4后,其7天的细胞转化率与采用传统方法14天的阳性率相当,7天时即可使相关软骨因子表达量同14天传统诱导表达量相当,显著缩短了诱导周期。

Sign in to read the full text

Claim 1 is shown. Create a free account to read all 9 claims, the full description, all drawings, translations and legal status.

  • All claims
  • Technical field
  • Background
  • Summary
  • Drawing descriptions
  • Detailed description

External Resources