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一种将外源物质高效转染进免疫细胞的方法

InventionUnknown
23Claims · 5 independent
§ Ⅰ

Dossier Overview

Inventor

戴晓兵

Filing Date

Apr 30, 2019

Publication Date

Oct 27, 2026

IPC Classification

C12N 15/85 (2006.01)C12N 13/00 (2006.01)A61K 40/11 (2025.01)A61K 40/15 (2025.01)A61K 40/19 (2025.01)A61K 40/17 (2025.01)A61K 40/31 (2025.01)A61P 35/00 (2006.01)A61P 35/02 (2006.01)

本发明提供一种电转染装置,采用钛镀铂作为电转染电极材料,能够有效的克服常规铝电极在电转染时铝离子析出的技术问题;同时本发明提供一种电转染的系统,能够将待转染物质高效转染进免疫细胞中,同时本发明的电转染方法可用于CAR‑T细胞的制备,同时本发明的电转染方法还可以联合CRISPR/Cas9编辑系统进行通用型CAR‑T细胞的制备,为免疫治疗提供解决方案。

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