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基于人工智能的处方剂量优化方法、装置及存储介质
InventionUnknown
9Claims · 4 independent
§ Ⅰ
Dossier Overview
Inventor
李宁; 解博文; 赵汉青
Filing Date
Sep 1, 2026
Publication Date
Oct 27, 2026
IPC Classification
G16H 20/10 (2018.01)G16H 50/30 (2018.01)G16H 50/70 (2018.01)G06F 18/10 (2023.01)G06F 18/2415 (2023.01)G06F 18/27 (2023.01)G06N 20/20 (2019.01)G06N 3/0455 (2023.01)G06N 3/09 (2023.01)G06N 5/045 (2023.01)
本发明公开了一种处方剂量优化方法、装置及存储介质,属于临床决策支持技术领域。本方案将剂量适宜性划分为"剂量不足—剂量适宜—剂量过量"的有序多分类目标,提出基于累积概率比加权和的有序证据权重编码,将传统二分类评分卡扩展至有序多分类场景;对于药效学中呈U型关系的指标,以治疗窗中位值为界拆分为表征剂量不足风险的下侧子特征和表征剂量过量风险的上侧子特征,确保有序逻辑回归的比例优势假设成立。最终由评分卡给出减量/维持/增量的分级建议,兼具预测精度和完全可解释性,尤其适合华法林等窄治疗窗药物的个体化剂量优化。
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