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包含表皮调节素抑制剂的癌症免疫治疗用抗癌辅助剂及癌症转移抑制用组合物
InventionUnknown
10Claims · 2 independent
§ Ⅰ
Dossier Overview
Inventor
赵容范; 柳雅澜; 洪惠暻; 申镕在
Filing Date
Dec 31, 2024
Publication Date
Oct 27, 2026
IPC Classification
A61K 31/713 (2006.01)A61P 35/00 (2006.01)A61P 35/04 (2006.01)C12Q 1/6886 (2006.01)A61K 39/00 (2006.01)
本发明涉及一种包含表皮调节素(epiregulin;EREG)抑制剂的癌症免疫治疗用抗癌辅助剂及癌症转移抑制用组合物。本发明旨在提供一种组合物,该组合物以肿瘤相关巨噬细胞(TAM)的表皮调节素为靶标,诱导肿瘤相关巨噬细胞的极化变化,具体地,通过调节M2巨噬细胞的亚型来增加M1巨噬细胞的比率,从而具有抑制癌细胞增殖及转移的效果。
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