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GUIDED BONE REGENERATION MATERIAL, METHOD OF MAKING AND USES THEREOF

InventionPending
20Claims · 1 independent
§ Ⅰ

Dossier Overview

Inventor

Hai Ming WONG; Quan Li LI; Le ZHANG

IPC Classification

A61L 31/2A61L 31/4A61L 31/14A61L 31/16C8L 33/2

CPC Classification

A61L31/28A61L31/48A61L31/146A61L31/16C8L33/2A61L2300/406A61L2430/2

The present invention provides a guided bone regeneration (GBR) material with antibacterial properties. The GBR material is a multi-component material, including an eggshell membrane (ESM) which is functionalized by mineralization in the presence of low-molecular-weight polyacrylic acid (LPAA). Thus, the ESM therefore includes at least one mineral deposited therein, preferably, intrafibrillar deposition, for example apatite and effective amounts of LPAA. The mineralized GBR material is preferably porous, and has good mechanical properties. A method of making mineralized GBR material which preferably contains intrafibrillar mineralization is also provided.

Original (Chinese)

The present invention provides a guided bone regeneration (GBR) material with antibacterial properties. The GBR material is a multi-component material, including an eggshell membrane (ESM) which is functionalized by mineralization in the presence of low-molecular-weight polyacrylic acid (LPAA). Thus, the ESM therefore includes at least one mineral deposited therein, preferably, intrafibrillar deposition, for example apatite and effective amounts of LPAA. The mineralized GBR material is preferably porous, and has good mechanical properties. A method of making mineralized GBR material which preferably contains intrafibrillar mineralization is also provided.

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