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METHODS OF TREATING, AMELIORATING AND/OR PREVENTING WOUNDS

InventionPending
20Claims · 7 independent
§ Ⅰ

Dossier Overview

Inventor

Kara L. Spiller; Jessica M. Eager

IPC Classification

G1N 33/68A61K 35/50A61K 45/6A61P 1/4

CPC Classification

G1N33/6893A61K35/50A61K45/6A61P1/4G1N2333/523G1N2800/62G1N2800/52G1N2800/60

Described herein is method of treating, ameliorating and/or preventing a wound in a subject in need thereof. The method includes: collecting a first sample from the wound at a first timepoint and determining a first CCL1 (chemokine ligand 1) level in the first sample; administering to the subject a first treatment that promotes wound healing; collecting a second sample from the wound at a second timepoint after the first timepoint and determining a second CCL1 level in the second sample; and (a) if the second CCL1 level is higher than the first CCL1 level times a predetermined value, continuing the administration of the first treatment or discontinuing the first treatment, (b) if the second CCL1 level is equal to or lower than the CCL1 level times the predetermined value, administering to the subject a second treatment that promotes wound healing.

Original (Chinese)

Described herein is method of treating, ameliorating and/or preventing a wound in a subject in need thereof. The method includes: collecting a first sample from the wound at a first timepoint and determining a first CCL1 (chemokine ligand 1) level in the first sample; administering to the subject a first treatment that promotes wound healing; collecting a second sample from the wound at a second timepoint after the first timepoint and determining a second CCL1 level in the second sample; and (a) if the second CCL1 level is higher than the first CCL1 level times a predetermined value, continuing the administration of the first treatment or discontinuing the first treatment, (b) if the second CCL1 level is equal to or lower than the CCL1 level times the predetermined value, administering to the subject a second treatment that promotes wound healing.

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