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№ US20260001868A1Invention

Pending

HETEROCYCLIC COMPOUND CAPABLE OF INHIBITING PRMT5-MTA AND USE THEREOF

A nitrogen-containing heterocyclic compound represented by formula (I-a), or a stereoisomer, a deuterated compound, a solvate, a pharmaceutically acceptable salt or a eutectic crystal thereof, a pharmaceutical composition comprising same, and a use thereof in the preparation of a drug for treating/preventing PRMT5⋅MTA-mediated diseases, wherein each group in formula (I-a) is as defined in the description.

❖Xizang Haisco Pharmaceutical Co., Ltd.Yao LI; Haoliang ZHANG; Zongjun SHI; Jiancheng WANG; Long WANG; Naicheng GUI; Jingzheng ZHAO; Shuai HUANG; Pingming TANG; Chen ZHANG; Pangke YAN§ 3/16 ClaimsC7D 403/14, A61K 31/422, A61K 31/4375 +2211

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Original name record: Xizang Haisco Pharmaceutical Co., Ltd.

HETEROCYCLIC COMPOUND CAPABLE OF INHIBITING PRMT5-MTA AND USE THEREOF