HETEROCYCLIC COMPOUND CAPABLE OF INHIBITING PRMT5-MTA AND USE THEREOF
Dossier Overview
Applicant
Xizang Haisco Pharmaceutical Co., Ltd.
Inventor
Yao LI; Haoliang ZHANG; Zongjun SHI; Jiancheng WANG; Long WANG; Naicheng GUI; Jingzheng ZHAO; Shuai HUANG; Pingming TANG; Chen ZHANG; Pangke YAN
IPC Classification
CPC Classification
A nitrogen-containing heterocyclic compound represented by formula (I-a), or a stereoisomer, a deuterated compound, a solvate, a pharmaceutically acceptable salt or a eutectic crystal thereof, a pharmaceutical composition comprising same, and a use thereof in the preparation of a drug for treating/preventing PRMT5⋅MTA-mediated diseases, wherein each group in formula (I-a) is as defined in the description.
Original (Chinese)
A nitrogen-containing heterocyclic compound represented by formula (I-a), or a stereoisomer, a deuterated compound, a solvate, a pharmaceutically acceptable salt or a eutectic crystal thereof, a pharmaceutical composition comprising same, and a use thereof in the preparation of a drug for treating/preventing PRMT5⋅MTA-mediated diseases, wherein each group in formula (I-a) is as defined in the description.
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